Desmoglein 3 (Dsg3), also known as Cadherin family member 6 (CDHF6), is a member of the desmosomal cadherin family and plays a critical role in cell-cell adhesion. It is predominately expressed in stratified squamous epithelium, including the skin, oral mucosa, and esophagus. Desmoglein 3 has been characterized as the auto-antigen of pemphigus vulgaris (PV), a life-threatening autoimmune disease. Binding of anti-Desmoglein 3 autoantibodies causes the loss of cell-cell adhesion, which clinically manifests as blisters on the skin and oral mucosa, and histologically as suprabasilar acantholysis.
130 kDa pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen 130 kDa pemphigus vulgaris antigen homolog bal balding Cadherin family member 6 CDHF6 desmoglein 3 Desmoglein-3 DKFZp686P23184 Dsg3 PVA; Cadherin family member 6; Desmoglein-3; PVA
Cat # 17116343
100 µL
Cat # 13437114
100 ug
Cat # 16391265
100 µL
Cat # 15787165
0.025 ml
Cat # 13279198
100 µL
Cat # 17179495
100 µL
Cat # 15934745
100 µg
Cat # 15939907
100 µg
Cat # 10777033
100 µg
Cat # 15969907
100 µg
Cat # 15734444
25 ug
Cat # 13408865
500 ug
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25 ug
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50 ug
Cat # 11595582
50 µg
Cat # 16396654
100 µl
Cat # 17297903
100 µL
Cat # 15704347
0.1 ml
Cat # 16370795
100 µL
Cat # 16363625
100 µL
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